Apart from potentially preventing a particular disease, vaccines may cause persistent nonspecific effects that can affect a person’s lifetime survival.
In a review published on Dec. 26 in Vaccine, researchers found that non-live vaccines like influenza, COVID-19, hepatitis B, and diphtheria-tetanus-pertussis (DTaP) tend to cause adverse nonspecific effects (NSE), increasing a person’s risks of all-cause mortality and the potential risk of infections from diseases they are meant to protect against.
A live vaccine contains a weakened form of the pathogen, which is less virulent but capable of replicating in the body, thus mimicking the actual disease progression. Non-live vaccines use inactivated viruses, fragments, or genes of the pathogen to trigger an immune response without pathogen replication.
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