An Israeli biotech firm says it is nearing human trials for a breakthrough drug that could extend human lifespan by up to 30 percent by targeting the age-regulating protein SIRT-6, which the company says would also improve brain function, organ health, and overall vitality.
On Friday, Israeli news site N12 reported that Tel Aviv-based Sirtlab is preparing to launch clinical trials on a drug designed to stimulate SIRT-6, a protein associated with youth, vitality, and disease resistance. The treatment could be available within three years, pending successful trials and regulatory approval.
Professor Haim Cohen, the company’s chief scientist and head of the Sagol Institute for Longevity Research, said the compound has already restored SIRT-6 levels in test animals to those seen in young specimens — dramatically extending both lifespan and quality of life.
“When this protein is more active in old age, not only do you live longer — you live healthier,” Cohen explained. Benefits observed included sharper memory, improved liver function, and even renewed hair growth.
Animal studies showed older subjects with increased SIRT-6 function had energy, physical capabilities, and or gan resilience comparable to much younger animals. According to the team, this suggests aging itself — not just disease — can be slowed or partially reversed. […]
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